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How to Buy Ionis Pharmaceuticals, Inc. Common Stock (IONS) Stock

Compare 13 brokers offering IONS, check which offer overnight sessions, see options pricing, and compare fractional-share terms.

IONS
$44.45+$0.6350 (+1.45%)
Day range
$43.66 – $45.30
52-week range
$43.01 – $86.74
Volume
5.35M
Market cap
$7.40B
Exchange
XNAS
Asset class
common
Optionable
Yes
24-hour trading
7 brokers — verify symbol
Fractional shares
10 brokers — verify symbol
Tokenized
No
Market cap tier
mid

Where to buy IONS

13 brokers in our matrix offer IONS. Verify availability and current fees with each broker before trading.

BrokerCommissionFractionalExtendedOvernightOptionsOTC access
Charles Schwab (thinkorswim) logoCharles Schwab (thinkorswim)Review$0
Schwab Stock Slices, S&P 500 only, ≥ $5/slice, up to 30 at once
~1,130
$0.65Most (3/5)
E*TRADE (Morgan Stanley) logoE*TRADE (Morgan Stanley)Review$0 listed
~20
$0.65Most (4/5)
Fidelity logoFidelityReview$0
Stocks by the Slice, 7,000+ stocks/ETFs, from $1
$0.65Partial (2+0)
Firstrade logoFirstradeReview$0
~4,000+ tickers, ≥ $5
~1,200
$0Most (4/5)
Interactive Brokers logoInteractive BrokersReview$0 (Lite) / per-share (Pro)
~10,000
per-contract pricingFull
Merrill Edge logoMerrill EdgeReview$0
$0.65Most (3/5)
Moomoo logoMoomooReview$0
$0Limited only
Public.com logoPublic.comReview$0
rebate modelLimited only
Robinhood logoRobinhoodReview$0
≥ $1 stocks, market cap ≥ $25M
~1,134
$0None
SoFi Active Investing logoSoFi Active InvestingReview$0
$0Partial (1+2)
tastytrade logotastytradeReview$0 stocks
$1.00 open, $0 close (capped at $10 per leg)Limited only
TradeStation logoTradeStationReview$0 listed
$0.50 / $0.60Most (4/5)
Webull logoWebullReview$0
$0Limited only

24-Hour / Overnight trading

These brokers run an overnight session: Charles Schwab (thinkorswim), Interactive Brokers, Robinhood, E*TRADE (Morgan Stanley), Webull, Moomoo, Firstrade. Each publishes its own list of symbols admitted to that session, and those lists are typically limited to large-cap index members. We do not track them per symbol, so check whether IONSis on your broker’s list before planning an overnight order.

Overnight sessions route through ATSs, typically have wider spreads, accept limit orders only, and offer no guaranteed fills.

About Ionis Pharmaceuticals, Inc. Common Stock

Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis marked its first two independent launches in 2025 for Tryngolza (for FCS) and Dawnzera (for HAE).
Sector
PHARMACEUTICAL PREPARATIONS
Employees
1,402
Headquarters
CARLSBAD, CA
Listed
1991-05-17
Market cap
$7.40B

Frequently asked

Where can I buy Ionis Pharmaceuticals, Inc. Common Stock (IONS)?

IONS is offered by 13 brokers in our matrix, including Charles Schwab (thinkorswim), E*TRADE (Morgan Stanley), Fidelity, Firstrade, Interactive Brokers. Compare commissions, fractional eligibility, and overnight availability in the broker matrix above.

Can I buy IONS after hours or overnight?

Most brokers in the matrix support pre-market (4 AM–9:30 AM ET) and after-hours (4–8 PM ET) sessions. A true overnight session is offered by Charles Schwab (thinkorswim), Interactive Brokers, Robinhood, E*TRADE (Morgan Stanley), and others, but each admits only its own list of symbols — usually large-cap index members — so confirm IONS is eligible with your broker. Overnight sessions route through ATSs with wider spreads and limit orders only.

Does Robinhood offer IONS?

Yes. Robinhood offers IONS as a regular exchange-listed security.

Does Fidelity offer IONS?

Yes. Fidelity offers IONS as a regular exchange-listed security.

Does Webull offer IONS?

Yes. Webull offers IONS as a regular exchange-listed security.

Is IONS optionable?

Yes. IONS has listed options contracts. Per-contract pricing varies by broker — see the Options column in the matrix.

Is there a tokenized version of IONS?

Not in our current dataset. The tokenized stock universe (Kraken xStocks, Binance Alpha/Ondo, Robinhood EU, Hyperliquid HIP-3) is expanding quickly — we refresh quarterly.

Can I buy a fractional share of IONS?

10 brokers in the matrix offer fractional shares, but each restricts the feature to its own symbol universe — Schwab to the S&P 500, Robinhood to stocks above a market-cap floor, Fidelity to a 7,000-name list. Check the Fractional column above for each broker's scope and minimum, then confirm IONS qualifies.

Related reading

Background on the trading features that apply to IONS.