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How to Buy Ionis Pharmaceuticals, Inc. Common Stock (IONS) Stock

Compare 15 brokers offering IONS, check 24-hour trading availability, see options pricing, and confirm OTC tier access.

IONS
$0.0000−$75.06 (−100.00%)
Day range
$74.83 – $75.50
52-week range
$32.00 – $86.74
Volume
473
Market cap
$12.40B
Exchange
XNAS
Asset class
common
Optionable
Yes
24-hour trading
Yes
Fractional eligible
Yes
Tokenized
No
Market cap tier
large

Where to buy IONS

15 brokers in our matrix offer IONS (penny/OTC-friendly subset). Verify availability and current fees with each broker before trading.

BrokerCommissionFractionalExtendedOvernightOptionsOTCQXOTCQBPink Cur.Pink Ltd.GreySurchargeShort locate
Firstrade logoFirstradeReview$0
~4,000+ tickers, ≥ $5
~1,200
$0FullFullFullFullLimited—limited
Interactive Brokers logoInteractive BrokersReview$0 (Lite) / per-share (Pro)
~10,000
per-contract pricingFullFullFullFullFullPer-share pricing appliesbest
TradeStation logoTradeStationReview$0 listed
$0.50 / $0.60FullFullFullFullLimited$0.005/share OTC (TS Select/TS Go), $0 up to 10,000 sharesstrong
Charles Schwab (thinkorswim) logoCharles Schwab (thinkorswim)Review$0
Schwab Stock Slices, S&P 500 only, ≥ $5/slice, up to 30 at once
~1,130
$0.65FullFullFullLimitedLimitedVariable service fees on certain restrictedmoderate
E*TRADE (Morgan Stanley) logoE*TRADE (Morgan Stanley)Review$0 listed
~20
$0.65FullFullFullFullLimited$6.95 flat on penny stocksmoderate
Fidelity logoFidelityReview$0
Stocks by the Slice, 7,000+ stocks/ETFs, from $1
$0.65FullFullNoNoNo—limited
Merrill Edge logoMerrill EdgeReview$0
$0.65FullFullFullLimitedNo—none
Moomoo logoMoomooReview$0
$0LimitedLimitedLimitedNoNo—limited
Public.com logoPublic.comReview$0
rebate modelLimitedLimitedLimitedNoNo—none
SoFi Active Investing logoSoFi Active InvestingReview$0
$0FullLimitedLimitedNoNo—none
tastytrade logotastytradeReview$0 stocks
$1.00 open, $0 close (capped at $10 per leg)LimitedLimitedLimitedNoNo—limited
Webull logoWebullReview$0
$0LimitedLimitedLimitedNoNo—limited
CenterPoint Securities logoCenterPoint SecuritiesReviewPer-share (day-trader oriented)
per-contractFullFullFullFullFullPer-sharebest
Cobra Trading logoCobra TradingReviewPer-share (day-trader oriented)
per-contractFullFullFullFullFullPer-sharebest
SpeedTrader logoSpeedTraderReviewPer-share (day-trader oriented)
per-contractFullFullFullFullFullPer-sharebest

24-Hour / Overnight trading

IONS may be eligible for overnight trading via Charles Schwab (thinkorswim), Interactive Brokers, Robinhood, E*TRADE (Morgan Stanley), Webull, Moomoo, Firstrade. Each broker maintains its own eligibility list — confirm before placing an order.

Overnight sessions route through ATSs, typically have wider spreads, accept limit orders only, and offer no guaranteed fills.

Penny stock / OTC routing

IONS trades on the OTC markets. Broker support varies sharply by tier (OTCQX, OTCQB, Pink Current, Pink Limited, Grey). Fidelity and Robinhood exclude pink/grey entirely. For short-locate on small-caps, Interactive Brokers and the day-trader specialists (Cobra Trading, SpeedTrader, CenterPoint) have the deepest inventory.

About Ionis Pharmaceuticals, Inc. Common Stock

Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis marked its first two independent launches in 2025 for Tryngolza (for FCS) and Dawnzera (for HAE).
Sector
PHARMACEUTICAL PREPARATIONS
Employees
1,402
Headquarters
CARLSBAD, CA
Listed
1991-05-17
Market cap
$12.40B

Frequently asked

Where can I buy Ionis Pharmaceuticals, Inc. Common Stock (IONS)?

IONS is offered by 15 brokers in our matrix, including Firstrade, Interactive Brokers, TradeStation, Charles Schwab (thinkorswim), E*TRADE (Morgan Stanley). Compare commissions, fractional eligibility, and overnight availability in the broker matrix above.

Can I buy IONS after hours or overnight?

Yes. IONS is on the 24-hour eligibility list for Charles Schwab (thinkorswim), Interactive Brokers, Robinhood, E*TRADE (Morgan Stanley), and others. Overnight sessions route through ATSs with wider spreads and limit-orders only.

Does Robinhood offer IONS?

No. Robinhood does not provide access to the OTC tier IONS trades on. Interactive Brokers, TradeStation, and Firstrade have the broadest OTC coverage.

Does Fidelity offer IONS?

Partial. Fidelity's OTC access is tier-limited — see the OTC columns in the matrix to check whether IONS's specific tier is supported.

Does Webull offer IONS?

Partial. Webull's OTC access is tier-limited — see the OTC columns in the matrix to check whether IONS's specific tier is supported.

Is IONS optionable?

Yes. IONS has listed options contracts. Per-contract pricing varies by broker — see the Options column in the matrix.

Is there a tokenized version of IONS?

Not in our current dataset. The tokenized stock universe (Kraken xStocks, Binance Alpha/Ondo, Robinhood EU, Hyperliquid HIP-3) is expanding quickly — we refresh quarterly.

Can I buy a fractional share of IONS?

Yes. Multiple brokers in the matrix support fractional shares for IONS — see the Fractional column above for per-broker eligibility and minimums.