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How to Buy Spruce Biosciences, Inc. Common Stock (SPRB) Stock

Compare 13 brokers offering SPRB, check which offer overnight sessions, and compare fractional-share terms.

SPRB
$53.13−$0.7300 (−1.36%)
Day range
$51.75 – $61.00
52-week range
$7.26 – $240.00
Volume
72.6K
Market cap
$152.47M
Exchange
XNAS
Asset class
common
Optionable
No
24-hour trading
7 brokers — verify symbol
Fractional shares
10 brokers — verify symbol
Tokenized
No
Market cap tier
micro

Where to buy SPRB

13 brokers in our matrix offer SPRB. Verify availability and current fees with each broker before trading.

BrokerCommissionFractionalExtendedOvernightOptionsOTC access
Charles Schwab (thinkorswim) logoCharles Schwab (thinkorswim)Review$0
Schwab Stock Slices, S&P 500 only, ≥ $5/slice, up to 30 at once
~1,130
$0.65Most (3/5)
E*TRADE (Morgan Stanley) logoE*TRADE (Morgan Stanley)Review$0 listed
~20
$0.65Most (4/5)
Fidelity logoFidelityReview$0
Stocks by the Slice, 7,000+ stocks/ETFs, from $1
$0.65Partial (2+0)
Firstrade logoFirstradeReview$0
~4,000+ tickers, ≥ $5
~1,200
$0Most (4/5)
Interactive Brokers logoInteractive BrokersReview$0 (Lite) / per-share (Pro)
~10,000
per-contract pricingFull
Merrill Edge logoMerrill EdgeReview$0
$0.65Most (3/5)
Moomoo logoMoomooReview$0
$0Limited only
Public.com logoPublic.comReview$0
rebate modelLimited only
Robinhood logoRobinhoodReview$0
≥ $1 stocks, market cap ≥ $25M
~1,134
$0None
SoFi Active Investing logoSoFi Active InvestingReview$0
$0Partial (1+2)
tastytrade logotastytradeReview$0 stocks
$1.00 open, $0 close (capped at $10 per leg)Limited only
TradeStation logoTradeStationReview$0 listed
$0.50 / $0.60Most (4/5)
Webull logoWebullReview$0
$0Limited only

24-Hour / Overnight trading

These brokers run an overnight session: Charles Schwab (thinkorswim), Interactive Brokers, Robinhood, E*TRADE (Morgan Stanley), Webull, Moomoo, Firstrade. Each publishes its own list of symbols admitted to that session, and those lists are typically limited to large-cap index members. We do not track them per symbol, so check whether SPRBis on your broker’s list before planning an overnight order.

Overnight sessions route through ATSs, typically have wider spreads, accept limit orders only, and offer no guaranteed fills.

About Spruce Biosciences, Inc. Common Stock

Spruce Biosciences Inc is a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare endocrine disorders with unmet medical needs. The company develops biologics and small-molecule product candidates aimed at addressing diseases with unmet medical needs and limited or no approved therapies. Its product candidate, TA-ERT for the treatment of Mucopolysaccharidosis Type IIIB (MPS IIIB), is a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase (rhNAGLU) intended as an enzyme replacement therapy for patients who lack rhNAGLU enzyme activity. TA-ERT is designed to restore rhNAGLU enzyme activity in the central nervous system following intracerebroventricular injection and promote clearance of heparan sulfate in the brain.
Sector
PHARMACEUTICAL PREPARATIONS
Employees
8
Headquarters
SOUTH SAN FRANCISCO, CA
Listed
2020-10-09
Market cap
$152.47M

Frequently asked

Where can I buy Spruce Biosciences, Inc. Common Stock (SPRB)?

SPRB is offered by 13 brokers in our matrix, including Charles Schwab (thinkorswim), E*TRADE (Morgan Stanley), Fidelity, Firstrade, Interactive Brokers. Compare commissions, fractional eligibility, and overnight availability in the broker matrix above.

Can I buy SPRB after hours or overnight?

Most brokers in the matrix support pre-market (4 AM–9:30 AM ET) and after-hours (4–8 PM ET) sessions. A true overnight session is offered by Charles Schwab (thinkorswim), Interactive Brokers, Robinhood, E*TRADE (Morgan Stanley), and others, but each admits only its own list of symbols — usually large-cap index members — so confirm SPRB is eligible with your broker. Overnight sessions route through ATSs with wider spreads and limit orders only.

Does Robinhood offer SPRB?

Yes. Robinhood offers SPRB as a regular exchange-listed security.

Does Fidelity offer SPRB?

Yes. Fidelity offers SPRB as a regular exchange-listed security.

Does Webull offer SPRB?

Yes. Webull offers SPRB as a regular exchange-listed security.

Is SPRB optionable?

No. SPRB does not have listed options contracts at the moment.

Is there a tokenized version of SPRB?

Not in our current dataset. The tokenized stock universe (Kraken xStocks, Binance Alpha/Ondo, Robinhood EU, Hyperliquid HIP-3) is expanding quickly — we refresh quarterly.

Can I buy a fractional share of SPRB?

10 brokers in the matrix offer fractional shares, but each restricts the feature to its own symbol universe — Schwab to the S&P 500, Robinhood to stocks above a market-cap floor, Fidelity to a 7,000-name list. Check the Fractional column above for each broker's scope and minimum, then confirm SPRB qualifies.

Related reading

Background on the trading features that apply to SPRB.